TOP MEDICAL JOURNALS

Trials is an open access, peer-reviewed, online journal that will encompass all aspects of the performance and findings of randomized controlled trials. Trials will experiment with, and then refine, innovative approaches to improving communication about trials. We are keen to move beyond publishing traditional trial results articles (although these will be included). We believe this represents an exciting opportunity to advance the science and reporting of trials. Prior to 2006, Trials was published as Current Controlled Trials in Cardiovascular Medicine (CCTCVM). All published CCTCVM articles are available via the Trials website and citations to CCTCVM article URLs will continue to be supported.
Making all its content open access and not retaining copyright, Trials offers a way to make data both freely available and highly visible to trialists worldwide; this will benefit the impact of your publication among peers and society. The journal has unrestricted space and takes advantage of all the technical possibilities available for electronic publishing.
To date, journals have focused on reporting the results of trials, with very little coverage of why and how they are conducted. Reports of trials have been restricted both by authors and editors - both parties often select only a subset of the outcomes measured, while the latter often impose word limits on the articles published making it difficult to communicate the lessons learnt from conducting the trial, let alone include adequate details of how the trial was conducted.

The Internet offers both unlimited space and interactivity, and we are keen to harness these attributes. For instance, trialists will be able to provide the detail required to be a true scientific record and do more to make the article’s message comprehensible to a variety of reader groups. They will also be able to communicate not only all outcome measures, as well as varying analyses and interpretations, but also in-depth descriptions of what they did and what they learnt. This sharing of direct experience is fundamental to improving the quality and conduct of trials worldwide.

status : FREE MEDICAL JOURNALS

The Archives of Internal Medicine is a bi-monthly international peer-reviewed professional medical journal published by the American Medical Association. Archives of Internal Medicine, begun in 1908, publishes original, peer-reviewed manuscripts on a full spectrum of internal medicine topics including cardiovascular disease, geriatrics, infectious disease, gastroenterology, endocrinology, allergy, and immunology.

The Archives of Internal Medicine, which publishes 22 times per year, has a a print circulation of over 100 000 physicians in 75 countries. The Archives of Internal Medicine’s recent acceptance rate is about 10%. The average time from receipt to first decision is 12 days; from receipt to final decision, 14 days; from submission to publication, 152 days. The Editor of the Archives of Internal Medicine is Philip Greenland, MD, Executive Associate Dean, Clinical and Translational Research, Northwestern University Feinberg School of Medicine, Chicago, Ill (see Archives Editorial Board).

Nature Medicine is an academic journal publishing research articles, reviews, news and commentaries in the biomedical area, including both basic research and early-phase clinical research. Topics covered include cancer, cardiovascular disease, gene therapy, immunology, vaccines and neuroscience. The journal seeks to publish research papers that ‘demonstrate novel insight into disease processes, with direct evidence of the physiological relevance of the results.
Founded in 1995, Nature Medicine is published by the Nature Publishing Group, a division of Macmillan Publishers Ltd, and is one of the rapidly expanding stable of Nature journals. Like other Nature journals, there is no external Editorial Board, with editorial decisions being made by an in-house team, although peer review by external expert referees forms a part of the review process. Nature Medicine is published monthly. Articles are archived online in text and PDF formats; access is by subscription only.

status :  requires a subscription or payment

Journal of Negative Results in Biomedicine is an Open Access, peer-reviewed, online journal that promotes a discussion of unexpected, controversial, provocative and/or negative results in the context of current tenets.

Journal of Negative Results in Biomedicine aims to encourage scientists and physicians of all fields to publish results that challenge current models, tenets or dogmas. The journal invites scientists and physicians to submit work that illustrates how commonly used methods and techniques are unsuitable for studying a particular phenomenon. Journal of Negative Results in Biomedicine strongly promotes and invites the publication of clinical trials that fall short of demonstrating an improvement over current treatments. The aim of the journal is to provide scientists and physicians with responsible and balanced information in order to improve experimental designs and clinical decisions.

Articles published in traditional journals frequently provide insufficient evidence regarding negative data. They hardly allow a rigorous evaluation of the quality of these results. In addition, controversial results that refute a current model or simply negative results within a current dogma, frequently meet considerable resistance before they are acknowledged. This is particularly the case if current techniques and technologies are too crude to shed further light on the findings. As more sophisticated techniques become available such findings may turn out to have been groundbreaking only decades later.

Not every unexpected observation, controversial conclusion or proposed model will turn out to be of such groundbreaking significance. Nor will they even be confirmed by subsequent scientific progress. However, we strongly believe that such “negative” observations and conclusions, based on rigorous experimentation and thorough documentation, ought to be published in order to be discussed, confirmed or refuted by others. In addition, publishing well documented failures may reveal fundamental flaws and obstacles in commonly used methods, drugs or reagents such as antibodies or cell lines, ultimately leading to improvements in experimental designs and clinical decisions.

status :  OPEN ACCESS JOURNALS